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Evidence-based GLP-1 & peptide discussion since 2023
ForumsSide Effects & ManagementKidney stone risk on GLP-1 — 6 month update Page 2

Kidney stone risk on GLP-1 — 6 month update

steve_okc Sat, Sep 13, 2025 at 5:29 AM 12 replies 1,200 viewsPage 2 of 3
LipidDoc_ATL
Senior Member
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Apr 2024
Atlanta, GA
Sep 13, 2025 at 8:19 AM#6
kate.chem said:
I have been dealing with this for over a year now, and what I have found is that individual response

Gonna push back on this one. Kidney stone risk on GLP-1 6 month is not that straightforward in my experience. I have been on this for 12 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But cost accessibility is a real barrier. We should be honest about that.

35 23rachel_ABQ, traveltech_sara, AttorneyGrant and 32 others
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Dr.NateNeph
VIP Member
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Dec 2023
Houston, TX
Sep 13, 2025 at 8:36 AM#7

Adding my data to this Kidney stone risk on discussion:

MetricBaselineMonth 5Month 6
Weight264 lbs224 lbs209 lbs
A1C6.8%6.0%5.2%
hsCRP8.04.00.6

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.6g/kg/day.

11 19NauseaFreeNow, SteveThurs, B12Beth and 8 others
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marcus_mpls
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Nov 2024
Minneapolis, MN
Sep 13, 2025 at 8:53 AM#8

Dr.BariatricHTX — wow. This community is amazing.

44 10tane_welly, Dr.PathRoch, mona_PHX and 41 others
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DanielChem_CHI
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Mar 2024
Chicago, IL
Sep 13, 2025 at 9:10 AM#9

Slightly tangential to Kidney stone risk on but WendyG_ATL reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

22 0ben_calgary, patPC_UT, Dr.DermMIA and 19 others
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mike_mod
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Sep 13, 2025 at 9:27 AM#10

Moderator note: Please keep vendor-specific discussions in the Vendor Reviews section.

I have cleaned up a few off-topic posts. 👍

50 9PurityPaulOR, MaxMetOK, MounjBrad and 47 others
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