Relevant to 100 lbs lost in 14 months 12 — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 193 → 93 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Want to share my personal experience related to 100 lbs lost in 14 months 12 since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 279 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 8 months later: I am down 79 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The 100 lbs lost in 14 aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on 100 lbs lost in 14 months.

To answer claudia_zurich: my doctor and I discussed the options and went with brand.

Quick update: I have noticed more improvement since posting this. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Want to share my personal experience related to 100 lbs lost in 14 months 12 since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 251 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 14 months later: I am down 86 lbs, my labs have normalized, and I am off 2 of my 3 medications. The 100 lbs lost in 14 aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

Dr.PathRoch — that is really helpful context on 100 lbs lost in 14 months. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.