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ForumsMASH / Liver DiseaseMASH biomarker panel — looking for input Page 3

MASH biomarker panel — looking for input

tammy_FL Sun, Jan 19, 2025 at 3:46 PM 31 replies 2,203 viewsPage 3 of 7
mike_mod
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Jan 19, 2025 at 8:01 PM#11

Moderator note: This thread has been getting great engagement. Please remember to cite sources when making clinical claims.

No issues to report — carry on. 👍

42 9PharmHunterJen, TomTeleRx, DoseLogDan and 39 others
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claudia_zurich
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Jan 19, 2025 at 8:18 PM#12

As a pharmacist, I want to add some clinical context to this discussion on MASH biomarker panel looking for input.

Building on what tammy_FL said — the evidence base here is robust. The key publications to reference are from the SUSTAIN program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
14 4tammy_FL, Dr.LipidDallas, alex_tucson and 11 others
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FDA_TrackerJim
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Jan 19, 2025 at 8:35 PM#13
mike_mod said:
Please remember to cite sources when making clinical claims

Gonna push back on this one. MASH biomarker panel looking for is not that straightforward in my experience. I have been on this for 12 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But cost accessibility is a real barrier. We should be honest about that.

Last edited: Jan 19, 2025 at 11:35 PM
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hans_munich
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Jan 19, 2025 at 8:52 PM#14

Want to share my personal experience related to MASH biomarker panel looking since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 269 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 14 months later: I am down 59 lbs, my labs have normalized, and I am off 2 of my 3 medications. The MASH biomarker panel aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

48 6tammy_FL, Dr.LipidDallas, alex_tucson and 45 others
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Dr.GastroMayo
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Jan 19, 2025 at 9:09 PM#15

Saving this for reference. Top-tier content.

50 20InsuranceTom, WendyG_ATL, SaraMom3 and 47 others
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