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ForumsProgress & Lab ResultsMonthly weigh-in thread — looking for input Page 2

Monthly weigh-in thread — looking for input

Dr.DermMIA Thu, Oct 2, 2025 at 11:44 AM 8 replies 986 viewsPage 2 of 2
KarenAZ_mom
Member
567
2,567
Aug 2024
Scottsdale, AZ
Oct 2, 2025 at 2:34 PM#6

SW: 271 / CW: 271 / GW: 200
Month 1, semaglutide 0.25mg
This month: 0 lbs

Yeah. A whole month and nothing. I know 0.25 is the starter dose and all that but it's hard not to feel like it's not working. I have my follow-up next week to go to 0.5. Is it normal to lose literally nothing on 0.25?

4 10anna.melb_AU, mark_tokyo, hans_munich and 1 other
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mike.trainer_LA
Senior Member
1,567
7,234
Apr 2024
Los Angeles, CA
Oct 2, 2025 at 2:51 PM#7

Completely normal. 0.25mg is genuinely a tolerability dose — it's below the therapeutic threshold for weight loss. Many people don't see meaningful appetite suppression until 1.0mg or higher. I lost 2 lbs in my first month and then 6 lbs in month 2 when I went to 0.5mg. The patience is brutal but the 0.25 step exists for a good reason (minimizing GI side effects).

15 0newstart_MO, mia_MS2, LeilaHI and 12 others
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stefan_berlin
Member
234
1,123
Oct 2024
Berlin, DE
Oct 2, 2025 at 3:08 PM#8

SW: 246 / CW: 203 / GW: 190
Month 7, semaglutide 2.4mg
This month: -3 lbs

Definitely in the "slow and steady" phase now. Loss rate has gone from 7 lbs/month early on to about 3-4 lbs/month. But the body comp is shifting nicely — waist is down another inch even though the scale only moved 3 lbs. Lifting 4x/week and eating 170g protein. Will do a DEXA next month.

Last edited: Oct 2, 2025 at 6:08 PM
34 21KevinCompounds, TirzTom, TrialTracker_MD and 31 others
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amsterdam_pete
Senior Member
1,567
6,789
Feb 2024
Netherlands
Oct 2, 2025 at 3:25 PM#9

SW: 196 / CW: 162 / GW: 150
Month 10, tirzepatide 7.5mg
This month: -1 lb

Getting close to goal weight and the loss has really slowed. But I feel amazing. A1C went from 6.2 to 5.3. I fit into clothes I wore in college. My husband says I look like I did when we started dating (flattering but also mildly annoying lol). Not sure if I'll go below 150 or just transition to maintenance here.

6 17KetoKyle, CanadaChris, ZaraB_AL and 3 others
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kim_atl_prep
Member
312
1,345
Aug 2024
Atlanta, GA
Oct 2, 2025 at 3:42 PM#10

SW: 308 / CW: 296 / GW: 220
Week 3, semaglutide 0.25mg
This month: -12 lbs

I know a lot of this is water weight but WOW. I haven't lost 12 lbs in a month doing anything, ever. The appetite suppression kicked in almost immediately for me. I went from eating 3,000+ calories to being full on 1,500 without even trying. Is this normal?? It almost feels too easy right now.

37 14PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 34 others
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