🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsSide Effects & ManagementWhen to stop GLP-1 — need advice Page 3

When to stop GLP-1 — need advice

pam_stl Fri, Jul 25, 2025 at 2:04 AM 39 replies 1,952 viewsPage 3 of 8
Admin
Administrator
2,456
9,812
Oct 2023
Online
Jul 25, 2025 at 6:19 AM#11

Moderator note: Great discussion, everyone. Just a reminder to keep things civil and evidence-based.

Thread quality is excellent — keep it up. 👍

Last edited: Jul 25, 2025 at 10:19 AM
32 6PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 29 others
Reply Quote Save Share Report
Dr.LeslieOBGYN
Member
567
2,567
May 2024
Dallas, TX
Jul 25, 2025 at 6:36 AM#12

Clinical perspective on When to stop GLP-1 need advice:

I have managed roughly 300 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

41 23FranDenver, Dr.BariatricHTX, LindaRN_retired and 38 others
Reply Quote Save Share Report
PharmacoVig_BOS
Senior Member
1,567
8,901
Feb 2024
Boston, MA
Jul 25, 2025 at 6:53 AM#13
Admin said:
Just a reminder to keep things civil and evidence-based

I respect Admin perspective but I think this oversimplifies things a bit. Re: When to stop GLP-1 need — the effect size varies considerably by population.

I am not saying Admin wrong entirely — just that the picture is more nuanced than a blanket statement. The STEP data specifically shows dose-dependent variation.

32 1DataDave, Dr.GutHealth, amsterdam_pete and 29 others
Reply Quote Save Share Report

Sigma-Aldrich — Research-Grade Standards

Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.

Shop Reference Standards
jennifer_SEA
Member
234
890
Nov 2024
Seattle, WA
Jul 25, 2025 at 7:10 AM#14

Reading this thread on When to stop GLP-1 need hits close to home. Dad of 2 checking in — I started at 273 lbs and felt like I would tried everything.

9 months on tirz and I am a different person. Not just the 48 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about When to stop GLP-1 — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Jul 25, 2025 at 1:10 PM
47 23jim_asheville, matt_MKE, Dr.ReproEndo and 44 others
Reply Quote Save Share Report
matt_MKE
Member
312
1,345
Sep 2024
Milwaukee, WI
Jul 25, 2025 at 7:27 AM#15

Bookmarked 📌 The When to stop GLP-1 info in this thread is essential. Coming back to this for sure.

27 23DanielChem_CHI, marco_milano, pam_columbus and 24 others
Reply Quote Save Share Report

Similar Threads

Nausea incidence by dose tier — STEP and SURMOUNT meta-analysis16 replies
Constipation on GLP-1: pathophysiology and fiber protocol5 replies
Alopecia on GLP-1 — telogen effluvium differential diagnosis3 replies
Gallbladder disease risk — cholelithiasis data from clinical trials12 replies
Pancreatitis risk assessment — pooled safety analysis15 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register