🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsSide Effects & ManagementWhen to stop GLP-1 — need advice Page 7

When to stop GLP-1 — need advice

pam_stl Fri, Jul 25, 2025 at 2:04 AM 39 replies 1,952 viewsPage 7 of 8
marcus_mpls
Member
234
1,123
Nov 2024
Minneapolis, MN
Jul 25, 2025 at 11:59 AM#31

Slightly tangential to When to stop GLP-1 need but Dr.SurgeonPGH reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

41 23bbq_ray_KC, oliver_london, tane_welly and 38 others
Reply Quote Save Share Report
mike_nyc
VIP Member
5,678
21,345
Nov 2023
New York
Online
Jul 25, 2025 at 12:16 PM#32

Saving this for reference. Top-tier content.

27 4stefan_berlin, Dr.EM_Chicago, pete_RVA and 24 others
Reply Quote Save Share Report
pam_stl
Member
267
1,123
Oct 2024
St. Louis, MO
Jul 25, 2025 at 12:33 PM#33

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on When to stop GLP-1 need.

To answer pam_stl: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Jul 25, 2025 at 5:33 PM
32 23PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 29 others
Reply Quote Save Share Report

Sigma-Aldrich — Research-Grade Standards

Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.

Shop Reference Standards
Dr.PathRoch
Member
456
2,123
Jun 2024
Rochester, MN
Jul 25, 2025 at 12:50 PM#34

Relevant to When to stop GLP-1 need — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 223 → 93 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Jul 25, 2025 at 6:50 PM
39 14SaraMom3, Dr.MetabolicMD, RetaRick_CA and 36 others
Reply Quote Save Share Report
FDA_TrackerJim
Senior Member
1,567
7,890
Feb 2024
Rockville, MD
Jul 25, 2025 at 1:07 PM#35

Want to share my personal experience related to When to stop GLP-1 need since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 264 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 6 months later: I am down 49 lbs, my labs have normalized, and I am off 2 of my 3 medications. The When to stop GLP-1 aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

26 6jason_paloalto, Dr.LeslieOBGYN, MikeNYC_runner and 23 others
Reply Quote Save Share Report

Similar Threads

Nausea incidence by dose tier — STEP and SURMOUNT meta-analysis16 replies
Constipation on GLP-1: pathophysiology and fiber protocol5 replies
Alopecia on GLP-1 — telogen effluvium differential diagnosis3 replies
Gallbladder disease risk — cholelithiasis data from clinical trials12 replies
Pancreatitis risk assessment — pooled safety analysis15 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register