Relevant to When to stop GLP-1 need — here is my latest bloodwork comparison:
Key improvements: A1C 8.4% → 5.5%, triglycerides 225 → 95 mg/dL, hsCRP 8.0 → 1.3 mg/L. All on tirzepatide for 17 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
Want to share my personal experience related to When to stop GLP-1 need since I think it might help others in a similar situation.
I started my GLP-1 journey in March 2025 at 281 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.
Now, 12 months later: I am down 56 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The When to stop GLP-1 aspect specifically was something that made a big difference in my journey.
This forum was my go-to resource throughout.
Dr.NateNeph — that is really helpful context on When to stop GLP-1 need. Follow-up question: did you change anything about your diet at the same time?
I am in a similar situation (month 2) and trying to set realistic expectations.
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Shop Reference StandardsWant to share my personal experience related to When to stop GLP-1 need since I think it might help others in a similar situation.
I started my GLP-1 journey in October 2024 at 253 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.
Now, 18 months later: I am down 63 lbs, my labs have normalized, and I am off 2 of my 3 medications. The When to stop GLP-1 aspect specifically was something that made a big difference in my journey.
This community helped me every step of the way.
Dr.NateNeph — that is really helpful context on When to stop GLP-1 need. Follow-up question: did you experience any side effects during this phase?
I am in a similar situation (about to start) and trying to set realistic expectations.