From 310 to 198 in 15 months — what worked for you? — Page 2

Dr.NutriCornell

Senior Member

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Mar 2024

Ithaca, NY

Sep 6, 2025 at 4:39 AM#6

Dr.SurgeonPGH said:
— in my experience this comes down to a few key factors

Gonna push back on this one. From 310 to 198 in 15 months what is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.

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anders_CPH

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Feb 2024

Copenhagen, DK

Sep 6, 2025 at 4:56 AM#7

Adding my data to this From 310 to 198 in 15 discussion:

Metric	Baseline	Month 5	Month 8
Weight	266 lbs	236 lbs	221 lbs
A1C	7.0%	6.0%	5.4%
hsCRP	5.0	4.0	0.8

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.3g/kg/day.

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LindaRN_retired

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Dec 2024

Sarasota, FL

Sep 6, 2025 at 5:13 AM#8

hyun_seoul — wow. I've been looking for this exact info for weeks.

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AttorneyGrant

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Apr 2024

Washington, DC

Sep 6, 2025 at 5:30 AM#9

Slightly tangential to From 310 to 198 in 15 but RegAffairsDC reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Sep 6, 2025 at 6:30 AM

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