Subscribing to this thread. Sleep apnea resolution is exactly what I've been researching. 🙏

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Sleep apnea resolution .

To answer Dr.LipidDallas: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Relevant to Sleep apnea resolution anyone — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 197 → 97 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

DataDave said:

Thank you all for the thoughtful replies on Sleep apnea resolution

This is exactly right. DataDave articulated what I have been trying to explain to my friends for months. The Sleep apnea resolution aspect is what made the difference for me.

Slightly tangential to Sleep apnea resolution but Dr.SleepRoch reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.