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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMASH / Liver DiseaseHas anyone dealt with mash resolution without worsening fibrosis? Page 6

Has anyone dealt with mash resolution without worsening fibrosis?

KevinCompounds Mon, Aug 5, 2024 at 11:40 AM 45 replies 2,606 viewsPage 6 of 9
AmyNC_wife
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Aug 5, 2024 at 8:10 PM#26

Congrats KevinCompounds!! Keep going — you're doing incredible. 🎉

37 2JessicaM_2024, TomFromTexas, mike.trainer_LA and 34 others
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Dr.ObesityMed
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Aug 5, 2024 at 8:27 PM#27

Slightly tangential to Has anyone dealt with but Admin reminded me — has the insurance landscape changed recently?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

36 23PharmacoVig_BOS, SurmountFan_IN, PeptideChemSF and 33 others
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Dr.SleepRoch
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Aug 5, 2024 at 8:44 PM#28

100%. My provider said the same thing about Has anyone dealt.

Last edited: Aug 6, 2024 at 12:44 AM
30 15Dr.NephBHM_UK, kim_atl_prep, sarah_TO and 27 others
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AttorneyGrant
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Aug 5, 2024 at 9:01 PM#29

Reading this thread on Has anyone dealt with hits close to home. Dad of 2 checking in — I started at 265 lbs and felt like I would tried everything.

11 months on tirz and I am a different person. Not just the 40 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Has anyone dealt — take the leap. It was the best health decision I have ever made. ❤️

46 14pat_auckland, Dr.GastroMayo, JakeBK_lifts and 43 others
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Dr.DermMIA
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Aug 5, 2024 at 9:18 PM#30

As a healthcare provider, I want to add some clinical context to this discussion on Has anyone dealt with mash resolution.

Building on what Dr.SleepRoch said — the evidence base here is well-established. The key publications to reference are from the SURMOUNT program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
42 5SurmountFan_IN, PeptideChemSF, A1cHero_PHX and 39 others
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