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ForumsMASH / Liver DiseaseLiver biopsy changes on semaglutide — looking for input Page 4

Liver biopsy changes on semaglutide — looking for input

Dr.GutHealth Wed, Jul 24, 2024 at 8:18 AM 29 replies 2,184 viewsPage 4 of 6
pete_RVA
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Jul 24, 2024 at 1:58 PM#16

Just wanted to say — for anyone reading this Liver biopsy changes thread who is feeling discouraged: it gets better. The first month are the hardest. Hang in there. 💪

Last edited: Jul 24, 2024 at 6:58 PM
9 7mike_mod, SarahChen_PharmD, sarah.morrison and 6 others
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SarahChen_PharmD
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Jul 24, 2024 at 2:15 PM#17

As a pharmacist, I want to add some clinical context to this discussion on Liver biopsy changes on semaglutide .

Building on what NurseAsh_DET said — the evidence base here is robust. The key publications to reference are from the STEP program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
Last edited: Jul 24, 2024 at 5:15 PM
38 20NurseKim_ATL, paul_denver, TinaHashiRN and 35 others
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Dr.SleepRoch
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Jul 24, 2024 at 2:32 PM#18
pete_RVA said:
The first month are the hardest

Gonna push back on this one. Liver biopsy changes on semaglutide is not that straightforward in my experience. I have been on this for 12 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But cost accessibility is a real barrier. We should be honest about that.

25 8Dr.NephBHM_UK, kim_atl_prep, sarah_TO and 22 others
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B12Beth
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Maryland
Jul 24, 2024 at 2:49 PM#19

Following this thread closely. Liver biopsy changes on is something I'm actively working through.

39 16marco_milano, pam_columbus, nick_SD_fit and 36 others
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julia.endo
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Jul 24, 2024 at 3:06 PM#20

Reading this thread on Liver biopsy changes on hits close to home. Night shift nurse — I started at 283 lbs and felt like I would tried everything.

9 months on tirz and I am a different person. Not just the 58 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Liver biopsy changes — take the leap. It was the best health decision I have ever made. ❤️

18 18chris_chi24, tampaLisa73, KarenAZ_mom and 15 others
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