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ForumsMASH / Liver DiseaseMASH prevalence in GLP-1 users — 6 month update

MASH prevalence in GLP-1 users — 6 month update

CryptoCarl Sat, Jun 29, 2024 at 4:37 PM 12 replies 1,822 viewsPage 1 of 3
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CryptoCarl
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Jun 29, 2024 at 6:02 PM#1

MASH prevalence in GLP-1 users — 6 month update

Saw this come across my feed today and thought the community would want to discuss.

MASH prevalence in GLP-1 users 6 is something that affects a lot of us here, and the latest information is worth paying attention to. I'll share what I know and hopefully others can fill in the gaps.

Key points as I understand them:

  • This has been evolving over the past few months
  • There are different perspectives on how to approach it
  • The practical implications depend on your specific situation

What are you all hearing from your providers about this? Anyone have direct experience to share?

12 19CryptoCarl, MariaRD, AussieAnna and 9 others
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HPLC_Greg
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Jun 29, 2024 at 6:19 PM#2

Good question. For MASH prevalence in GLP-1 users 6, here is what the evidence says:

  • The clinical trial data (SELECT program) supports this approach
  • Real-world results from this community generally confirm the trial findings
  • Individual variation is real — give it at least 8 weeks before judging

Happy to go deeper on any of these points if helpful.

Last edited: Jun 30, 2024 at 12:19 AM
42 24JenPlateau, SallyK_inj, CryptoCarl and 39 others
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josh_phd_bmore
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Jun 29, 2024 at 6:36 PM#3
HPLC_Greg said:
For MASH prevalence in GLP-1 users 6, here is what the evidence says:The clinical trial data (SELEC

Completely agree with HPLC_Greg. I would add that MASH prevalence in GLP-1 users also has implications for body composition that sometimes get overlooked in these discussions.

In my case, following a similar approach led to fewer side effects compared to what I was doing before.

35 14zoe_NC, Dr.ObesityLA, NurseKim_ATL and 32 others
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MounjBrad
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Jun 29, 2024 at 6:53 PM#4

Agreed. My doctor said the same thing about MASH prevalence in.

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anna.melb_AU
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Jun 29, 2024 at 7:10 PM#5

As a healthcare provider, I want to add some clinical context to this discussion on MASH prevalence in GLP-1 users 6 month.

Building on what CryptoCarl said — the evidence base here is well-established. The key publications to reference are from the SELECT program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
Last edited: Jun 29, 2024 at 11:10 PM
9 9Dr.LipidDallas, alex_tucson, kevin_tulsa and 6 others
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