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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCOA & Analytical TestingHas anyone dealt with are all coas created equal? mine looks different from others i see? Page 3

Has anyone dealt with are all coas created equal? mine looks different from others i see?

mel_PDX Fri, Nov 7, 2025 at 2:07 AM 31 replies 1,060 viewsPage 3 of 7
zoe_NC
Member
278
1,234
Nov 2024
Charlotte, NC
Nov 7, 2025 at 6:22 AM#11

Thank you pete_manc_UK! This is incredibly helpful. Taking this to my next appointment. 🙏

33 16Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 30 others
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sophie_paris
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890
Nov 2024
Paris, FR
Nov 7, 2025 at 6:39 AM#12

Slightly tangential to Has anyone dealt with are but mel_PDX reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

39 16CryptoCarl, MariaRD, AussieAnna and 36 others
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sean_dublin
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Nov 2024
Dublin, IE
Nov 7, 2025 at 6:56 AM#13

Thanks for sharing this, mel_PDX. A few questions about your Has anyone dealt experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about Has anyone deal?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

Last edited: Nov 7, 2025 at 7:56 AM
27 15gary_naperville, sean_dublin, hannah_MT and 24 others
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mel_PDX
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890
Dec 2024
Portland, OR
Nov 7, 2025 at 7:13 AM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Has anyone dealt with are.

To answer sophie_paris: I started tracking everything in a spreadsheet from day 1.

Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

7 6BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 4 others
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Dr.PathRoch
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456
2,123
Jun 2024
Rochester, MN
Nov 7, 2025 at 7:30 AM#15

Adding my data to this Has anyone dealt with are discussion:

MetricBaselineMonth 3Month 8
Weight258 lbs218 lbs213 lbs
A1C7.2%5.8%5.4%
hsCRP7.02.00.8

Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.5g/kg/day.

Last edited: Nov 7, 2025 at 1:30 PM
33 12Dr.MetabolicMD, RetaRick_CA, JenPlateau and 30 others
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