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ForumsMASH / Liver DiseaseHepatic steatosis grading on ultrasound — 6 month update

Hepatic steatosis grading on ultrasound — 6 month update

pete_manc_UK Mon, Mar 18, 2024 at 2:26 AM 16 replies 1,944 viewsPage 1 of 4
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pete_manc_UK
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Mar 18, 2024 at 3:51 AM#1

Quick question for the group — hepatic steatosis grading on ultrasound 6.

I searched before posting (promise!) but the threads I found were from a few months back and things seem to have changed since then.

My situation: I'm about 4 months in and this came up during my last appointment. My pharmacist mentioned it but did not go into detail.

Would love to hear from people who've actually dealt with this. What worked? What didn't? What do you wish someone had told you?

Thanks everyone — this forum has been invaluable for me.

19 2TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 16 others
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BethLabQueen
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Mar 18, 2024 at 4:08 AM#2

pete_manc_UK's experience with Hepatic steatosis grading resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.

The main difference: I titrated faster. But the overall trajectory has been remarkably similar. Down 52 lbs in 7 months.

One thing I would add that pete_manc_UK did not mention: the relationship with food fundamentally changed.

Last edited: Mar 18, 2024 at 5:08 AM
12 3Dr.PulmRoch, maya_sedona, stefan_berlin and 9 others
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LabKate
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Mar 18, 2024 at 4:25 AM#3

Thanks for sharing this, pete_manc_UK. A few questions about your Hepatic steatosis experience:

  1. What dose are you currently on?
  2. How long before you noticed significant changes?
  3. Did your doctor have any specific recommendations about Hepatic steatos?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

30 1Dr.SleepRoch, laura_annarbor, JenMemphis and 27 others
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pete_manc_UK
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Mar 18, 2024 at 4:42 AM#4

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Hepatic steatosis grading.

To answer LabKate: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

21 19sarah_nash92, FitDadDave, RunnerRach and 18 others
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labquiet_amy
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Mar 18, 2024 at 4:59 AM#5

Relevant to Hepatic steatosis grading on — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 225 → 95 mg/dL, hsCRP 8.0 → 1.3 mg/L. All on tirzepatide for 17 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

23 4pete_manc_UK, anna.melb_AU, mark_tokyo and 20 others
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