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ForumsSide Effects & ManagementDiarrhea vs constipation on GLP-1 — need advice Page 2

Diarrhea vs constipation on GLP-1 — need advice

BenResearch_OR Wed, Dec 18, 2024 at 9:12 PM 50 replies 2,016 viewsPage 2 of 10
JenPlateau
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Dec 19, 2024 at 12:02 AM#6

Glad it resolved. A few additional points for everyone reading this later:

When constipation on GLP-1s requires medical attention:

  • No BM for 7+ days despite OTC interventions
  • Severe abdominal pain or distension
  • Vomiting (could indicate obstruction)
  • Blood in stool or rectal bleeding
  • Fecal impaction symptoms (constant urge, inability to pass, leaking of liquid stool around impaction)

Also — and I say this gently — make sure you're actually eating enough. Some patients get so focused on appetite suppression that they're consuming <800 calories and barely any fiber. Your colon needs bulk to work with. Even on a GLP-1, aim for 20-25g of fiber daily.

Last edited: Dec 19, 2024 at 6:02 AM
49 14HPLC_Greg, LibrarianMeg, bri_stats and 46 others
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Dr.RaviCardio
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New York, NY
Dec 19, 2024 at 12:19 AM#7

Adding my two cents: a squatty potty (or any footstool that gets your knees above your hips) made a real difference for me. Changes the angle of the anorectal junction. Combined with Miralax it went from "impossible" to "manageable."

Also seconding the walking recommendation. On days I walk 30+ minutes, things move. On days I sit at my desk all day, nothing.

Last edited: Dec 19, 2024 at 1:19 AM
48 9anna.melb_AU, mark_tokyo, hans_munich and 45 others
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NeuroNate
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Dec 2023
Chicago, IL
Dec 19, 2024 at 12:36 AM#8

One more underrated tip: warm beverages. Hot coffee in the morning has a well-documented prokinetic effect on the colon. Even if the drug is slowing your GI tract, caffeine and the gastrocolic reflex from warm liquid can help kickstart things. I have a cup of hot coffee within 20 minutes of waking up and it's the most reliable part of my constipation management.

33 14sarah_TO, wendy_avl, jason_paloalto and 30 others
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