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Evidence-based GLP-1 & peptide discussion since 2023
ForumsExercise & Body CompositionThrew up at the gym on injection day - lesson learned — looking for input Page 3

Threw up at the gym on injection day - lesson learned — looking for input

pete_nash Sun, Nov 12, 2023 at 2:56 PM 63 replies 2,517 viewsPage 3 of 13
CarlaRPh_TPA
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Nov 12, 2023 at 7:11 PM#11

+1 to SarahChen_PharmD. Especially the point about "Re: Threw up at the gym on — the subgrou..." — I have seen the same in my own experience with Threw up at the gym on.

6 3FDA_TrackerJim, ricardo_MIA, BrianDallas92 and 3 others
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ingrid_STO
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Stockholm, SE
Nov 12, 2023 at 7:28 PM#12

Want to share my personal experience related to Threw up at the gym on since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 276 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 16 months later: I am down 61 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Threw up at the gym aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

1 9COA_Karl
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BiostatsBrad
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Nov 12, 2023 at 7:45 PM#13

Dr.CardioMD — that is really helpful context on Threw up at the gym on. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

46 10FranDenver, Dr.BariatricHTX, LindaRN_retired and 43 others
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Dr.PulmRoch
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Rochester, MN
Nov 12, 2023 at 8:02 PM#14

To answer ingrid_STO's question specifically:

From a clinical standpoint, Threw up at the gym on is well-supported by the literature.

The short answer: follow the standard titration protocol and reassess at 4-6 weeks.

The longer answer involves pharmacokinetic considerations around steady-state concentrations, which I am happy to elaborate on if helpful.

48 19DebRD_ATL, KristenIndy, MarkLI_maint and 45 others
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Dr.NateNeph
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Nov 12, 2023 at 8:19 PM#15

Saving this for reference. Top-tier content.

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