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ForumsMASH / Liver DiseaseQuit drinking AND started sema - liver is thanking me — looking for input Page 3

Quit drinking AND started sema - liver is thanking me — looking for input

Dr.LipidDallas Tue, Dec 26, 2023 at 4:23 AM 48 replies 2,428 viewsPage 3 of 10
mike_mod
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Dec 26, 2023 at 8:38 AM#11

Moderator note: Please keep vendor-specific discussions in the Vendor Reviews section.

I have cleaned up a few off-topic posts. 👍

44 14PharmHunterJen, TomTeleRx, DoseLogDan and 41 others
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Dr.Martinez
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Dec 26, 2023 at 8:55 AM#12

As a healthcare provider, I want to add some clinical context to this discussion on Quit drinking AND started sema - liver.

Building on what Dr.LipidDallas said — the evidence base here is well-established. The key publications to reference are from the SURMOUNT program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
36 1traveltech_sara, AttorneyGrant, DebRD_ATL and 33 others
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LipidDoc_ATL
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Dec 26, 2023 at 9:12 AM#13
mike_mod said:
I have cleaned up a few off-topic posts

Gonna push back on this one. Quit drinking AND started sema - is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.

21 5AttorneyGrant, DebRD_ATL, KristenIndy and 18 others
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jason_sac26
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Dec 26, 2023 at 9:29 AM#14

Want to share my personal experience related to Quit drinking AND started sema since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 253 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 14 months later: I am down 83 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Quit drinking AND aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

28 17maya_sedona, stefan_berlin, Dr.EM_Chicago and 25 others
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pat_auckland
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Dec 26, 2023 at 9:46 AM#15

Saving this for reference. Quality thread.

35 7dan_philly, MeganSA_TX, LarryQC_SD and 32 others
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