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ForumsMASH / Liver DiseaseSemaglutide and MASH — 6 month update Page 3

Semaglutide and MASH — 6 month update

Dr.ReproEndo Mon, Nov 27, 2023 at 1:09 PM 11 replies 2,208 viewsPage 3 of 3
NurseAsh_DET
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Sep 2024
Detroit, MI
Nov 27, 2023 at 5:24 PM#11

ricardo_MIA — wow. This community is amazing.

Last edited: Nov 27, 2023 at 11:24 PM
26 2FDA_TrackerJim, ricardo_MIA, BrianDallas92 and 23 others
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quinn_sf
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Jun 2024
San Francisco, CA
Nov 27, 2023 at 5:41 PM#12

Slightly tangential to Semaglutide and MASH 6 but Dr.ReproEndo reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

30 18Dr.PathRoch, mona_PHX, andrew_nyc and 27 others
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pete_nash
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Aug 2024
Nashville, TN
Nov 27, 2023 at 5:58 PM#13

Thanks for sharing this, Dr.ReproEndo. A few questions about your Semaglutide and MASH experience:

  1. What dose worked best for you?
  2. How long before you noticed appetite suppression kicking in?
  3. Did your endo have any specific recommendations about Semaglutide and?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

16 0mike_mod, SarahChen_PharmD, sarah.morrison and 13 others
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Dr.ReproEndo
Senior Member
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Jan 2024
Scottsdale, AZ
Nov 27, 2023 at 6:15 PM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Semaglutide and MASH 6.

To answer quinn_sf: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

31 12GraceAZ_72, carl_compliance, DanielChem_CHI and 28 others
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NicoleRaleigh
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Aug 2024
Raleigh, NC
Nov 27, 2023 at 6:32 PM#15

Relevant to Semaglutide and MASH 6 month — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 209 → 109 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

13 1mike_nyc, VendorMark, COA_Karl and 10 others
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