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Evidence-based GLP-1 & peptide discussion since 2023
ForumsProgress & Lab ResultsFirst month - only lost 6 lbs, is that bad? — looking for input Page 3

First month - only lost 6 lbs, is that bad? — looking for input

fiona_VT Wed, Jan 8, 2025 at 10:35 AM 13 replies 1,656 viewsPage 3 of 3
SurmountFan_IN
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May 2024
Indianapolis, IN
Jan 8, 2025 at 2:50 PM#11

+1 to Dr.ObesityLA. Especially the point about "Re: First month - only lost 6 lbs, — the..." — I have seen the same in my own experience with First month - only lost 6.

Last edited: Jan 8, 2025 at 3:50 PM
18 2DebRD_ATL, KristenIndy, MarkLI_maint and 15 others
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chris_chi24
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Sep 2024
Chicago, IL
Jan 8, 2025 at 3:07 PM#12

Want to share my personal experience related to First month - only lost 6 lbs, since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 255 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 10 months later: I am down 65 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The First month - only aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

13 4MounjBrad, nick_newbie, DadBodDave and 10 others
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maya_sedona
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Sep 2024
Sedona, AZ
Jan 8, 2025 at 3:24 PM#13

PeptideChemSF — that is really helpful context on First month - only lost 6. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

35 9BenResearch_OR, MikeKY_noInsulin, Dr.RaviCardio and 32 others
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NurseAsh_DET
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Sep 2024
Detroit, MI
Jan 8, 2025 at 3:41 PM#14

To answer chris_chi24's question specifically:

From a clinical standpoint, First month - only lost 6 lbs, is well-supported by the literature.

The short answer: follow the standard titration protocol and reassess at 4-6 weeks.

The longer answer involves pharmacokinetic considerations around steady-state concentrations, which I am happy to elaborate on if helpful.

Last edited: Jan 8, 2025 at 9:41 PM
46 10labquiet_amy, emily_PDX, Dr.SleepRoch and 43 others
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andrew_nyc
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Jan 8, 2025 at 3:58 PM#15

Saving this for reference. Top-tier content.

50 23JessicaM_2024, TomFromTexas, mike.trainer_LA and 47 others
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