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ForumsSide Effects & ManagementWhen to stop GLP-1 — what worked for you?

When to stop GLP-1 — what worked for you?

oliver_london Fri, Aug 16, 2024 at 10:08 PM 14 replies 1,866 viewsPage 1 of 3
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oliver_london
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London, UK
Aug 16, 2024 at 11:33 PM#1

Can I just vent for a second about when to stop glp-1 what worked?

I know this forum is evidence-based and I love that about it, but sometimes you just need to let it out. I hit another plateau and I am frustrated.

Not looking for a fix necessarily — just solidarity. Anyone else going through this right now?

27 5Admin, Dr.Martinez, mike_mod and 24 others
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SarahChen_PharmD
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Aug 16, 2024 at 11:50 PM#2

oliver_london's experience with When to stop GLP-1 what resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.

The main difference: I started 3 months later. But the overall trajectory has been remarkably similar. Down 50 lbs in 5 months.

One thing I would add that oliver_london did not mention: the mental health improvements were just as significant.

40 6NurseKim_ATL, paul_denver, TinaHashiRN and 37 others
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TrialTracker_MD
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Aug 17, 2024 at 12:07 AM#3

Thanks for sharing this, oliver_london. A few questions about your When to stop GLP-1 experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about When to stop?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

24 2maya_sedona, stefan_berlin, Dr.EM_Chicago and 21 others
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oliver_london
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Aug 2024
London, UK
Aug 17, 2024 at 12:24 AM#4

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on When to stop GLP-1 what.

To answer TrialTracker_MD: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

31 13jason_paloalto, Dr.LeslieOBGYN, MikeNYC_runner and 28 others
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LabKate
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Aug 17, 2024 at 12:41 AM#5

Relevant to When to stop GLP-1 what — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 223 → 93 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

30 8labquiet_amy, emily_PDX, Dr.SleepRoch and 27 others
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