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Evidence-based GLP-1 & peptide discussion since 2023
ForumsProgress & Lab ResultsHas anyone dealt with 100 lbs lost in 14 months? Page 5

Has anyone dealt with 100 lbs lost in 14 months?

InsuranceTom Sat, Oct 26, 2024 at 12:58 AM 34 replies 2,180 viewsPage 5 of 7
JenMemphis
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Oct 26, 2024 at 8:03 AM#21

KevinCompounds — that is really helpful context on Has anyone dealt with 100. Follow-up question: how long did you wait before increasing your dose?

I am in a similar situation (week 4) and trying to set realistic expectations.

24 14MikeKY_noInsulin, Dr.RaviCardio, jennifer_SEA and 21 others
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Dr.PulmRoch
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Rochester, MN
Oct 26, 2024 at 8:20 AM#22

To answer FranDenver's question specifically:

From a clinical standpoint, Has anyone dealt with 100 lbs is a reasonable concern that deserves a thorough answer.

The short answer: the evidence supports this approach for most patients.

The longer answer involves reviewing the specific clinical trial data relevant to your question, which I am happy to elaborate on if helpful.

50 7traveltech_sara, AttorneyGrant, DebRD_ATL and 47 others
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TirzTom
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Oct 26, 2024 at 8:37 AM#23

Thank you JenMemphis! This is incredibly helpful. Taking this to my next appointment. 🙏

Last edited: Oct 26, 2024 at 12:37 PM
24 19Dr.EndoIndy, tom_AK, josh_phd_bmore and 21 others
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stefan_berlin
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Berlin, DE
Oct 26, 2024 at 8:54 AM#24

Relevant to Has anyone dealt with 100 lbs — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 243 → 113 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

43 24TirzTom, TrialTracker_MD, JennaRN and 40 others
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Dr.KarenChen
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Oct 26, 2024 at 9:11 AM#25

Slightly tangential to Has anyone dealt with 100 but JenMemphis reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Oct 26, 2024 at 3:11 PM
48 11sarah_nash92, FitDadDave, RunnerRach and 45 others
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