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ForumsCOA & Analytical TestingEndotoxin testing methods — what worked for you? Page 5

Endotoxin testing methods — what worked for you?

mona_PHX Mon, Apr 7, 2025 at 3:18 AM 29 replies 1,900 viewsPage 5 of 6
ricardo_MIA
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Apr 7, 2025 at 10:23 AM#21

pete_RVA — that is really helpful context on Endotoxin testing methods. Follow-up question: what labs did your doctor order to monitor this?

I am in a similar situation (just started) and trying to set realistic expectations.

1 15JakeSmashed95
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Dr.LeslieOBGYN
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May 2024
Dallas, TX
Apr 7, 2025 at 10:40 AM#22

To answer PharmD_Rodriguez's question specifically:

From a clinical standpoint, Endotoxin testing methods is an area where we have good evidence.

The short answer: baseline labs + quarterly monitoring is the standard of care.

The longer answer involves understanding the mechanism of action at the receptor level, which I am happy to elaborate on if helpful.

20 10FranDenver, Dr.BariatricHTX, LindaRN_retired and 17 others
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fiona_glasgow
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Glasgow, UK
Apr 7, 2025 at 10:57 AM#23

Thank you ricardo_MIA! This is incredibly helpful. Bookmarking for later. 🙏

Last edited: Apr 7, 2025 at 3:57 PM
25 7KevinCompounds, TirzTom, TrialTracker_MD and 22 others
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lucas_SP_BR
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São Paulo, BR
Apr 7, 2025 at 11:14 AM#24

Relevant to Endotoxin testing methods — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 213 → 113 mg/dL, hsCRP 8.0 → 1.3 mg/L. All on tirzepatide for 17 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

24 20KarenAZ_mom, zoe_NC, Dr.ObesityLA and 21 others
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TrialTracker_MD
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Apr 7, 2025 at 11:31 AM#25

Slightly tangential to Endotoxin testing methods but ricardo_MIA reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Apr 7, 2025 at 4:31 PM
22 11lori_vegas, Dr.PulmRoch, maya_sedona and 19 others
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