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ForumsSide Effects & ManagementFAERS pharmacovigilance data for semaglutide — anyone have experience? Page 3

FAERS pharmacovigilance data for semaglutide — anyone have experience?

bri_stats Mon, Dec 25, 2023 at 2:29 PM 36 replies 2,800 viewsPage 3 of 8
mike_mod
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Dec 25, 2023 at 6:44 PM#11

Moderator note: This thread has been getting great engagement. Please remember to cite sources when making clinical claims.

No issues to report — carry on. 👍

25 20PharmHunterJen, TomTeleRx, DoseLogDan and 22 others
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jim_asheville
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Dec 25, 2023 at 7:01 PM#12

As a pharmacist, I want to add some clinical context to this discussion on FAERS pharmacovigilance data for.

Building on what bri_stats said — the evidence base here is robust. The key publications to reference are from the SUSTAIN program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
25 22BenResearch_OR, MikeKY_noInsulin, Dr.RaviCardio and 22 others
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PharmacoVig_BOS
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Dec 25, 2023 at 7:18 PM#13
mike_mod said:
Please remember to cite sources when making clinical claims

Gonna push back on this one. FAERS pharmacovigilance data for is not that straightforward in my experience. I have been on this for 12 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But cost accessibility is a real barrier. We should be honest about that.

37 17DataDave, Dr.GutHealth, amsterdam_pete and 34 others
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ben_calgary
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Dec 25, 2023 at 7:35 PM#14

Want to share my personal experience related to FAERS pharmacovigilance data since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 289 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 18 months later: I am down 84 lbs, my labs have normalized, and I am off 2 of my 3 medications. The FAERS pharmacovigila aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

23 17JakeSmashed95, NauseaFreeNow, SteveThurs and 20 others
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Admin
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Dec 25, 2023 at 7:52 PM#15

Saving this for reference. Top-tier content.

Last edited: Dec 25, 2023 at 11:52 PM
50 23PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 47 others
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