OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Muscle cramps on.

To answer ChrisMacros: I started tracking everything in a spreadsheet from day 1.

Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Adding my data to this Muscle cramps on discussion:

Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.2g/kg/day.

Subscribing to this thread. Muscle cramps on is exactly what I've been researching. 🙏

Slightly tangential to Muscle cramps on but MikeNYC_runner reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

+1 to FDA_TrackerJim. Especially the point about "Thank you all for the thoughtful replies..." — I have seen the same in my own experience with Muscle cramps on.