Slightly tangential to 18-month transformation but rick_sfbay reminded me — does anyone have experience combining this with metformin?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
Thanks for sharing this, rick_sfbay. A few questions about your 18-month transformat experience:
- What dose did you start at?
- How long before you noticed side effects improving?
- Did your provider have any specific recommendations about 18-month transf?
I am in a similar boat and trying to learn from others' experiences before my next appointment.
Sigma-Aldrich — Research-Grade Standards
Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.
Shop Reference StandardsOP here — wow, did not expect this much response! Thank you all for the thoughtful replies on 18-month transformation .
To answer NeuroNate: I started tracking everything in a spreadsheet from day 1.
Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
Adding my data to this 18-month transformation discussion:
| Metric | Baseline | Month 3 | Month 8 |
|---|---|---|---|
| Weight | 242 lbs | 222 lbs | 207 lbs |
| A1C | 6.6% | 5.8% | 5.4% |
| hsCRP | 6.0 | 2.0 | 0.8 |
Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.4g/kg/day.