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ForumsSide Effects & ManagementAcid reflux/GERD worsening on GLP-1 — November 2025

Acid reflux/GERD worsening on GLP-1 — November 2025

JenMemphis Sat, Oct 14, 2023 at 2:00 AM 13 replies 2,113 viewsPage 1 of 3
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JenMemphis
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Jan 2025
Memphis, TN
Oct 14, 2023 at 3:25 AM#1

Update on my situation with acid reflux/gerd worsening on glp-1 november — wanted to follow up since some of you asked.

2 months since my last post and things have changed a lot. Here is what happened:

Talked to my provider about the concerns raised in my previous thread and they had a different perspective.

Full details below. Thanks to everyone who responded last time — your input genuinely made a difference.

34 8MikeKY_noInsulin, Dr.RaviCardio, jennifer_SEA and 31 others
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PurityPaulOR
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Oregon
Oct 14, 2023 at 3:42 AM#2

To answer the question about Acid reflux/GERD worsening on GLP-1 November 2025 — in my experience this comes down to a few key factors.

I have been dealing with this for over a year now, and what I have found is that individual responses really do vary. That said, the general consensus on Acid reflux/GERD worsening on seems solid.

What specifically worked for me: getting baseline labs before making any changes. I would suggest JenMemphis try the same approach and reporting back.

1 14MikeNYC_runner
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Dr.SportsMedIN
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Oct 14, 2023 at 3:59 AM#3
PurityPaulOR said:
I have been dealing with this for over a year now, and what I have found is that individual response

Completely agree with PurityPaulOR. I would add that Acid reflux/GERD worsening on also has implications for long-term metabolic health that sometimes get overlooked in these discussions.

In my case, following a similar approach led to significant improvements compared to what I was doing before.

Last edited: Oct 14, 2023 at 8:59 AM
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MikeNYC_runner
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Oct 14, 2023 at 4:16 AM#4

Subscribing to this thread. Acid reflux/GERD is exactly what I've been researching. 🙏

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sean_dublin
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Nov 2024
Dublin, IE
Oct 14, 2023 at 4:33 AM#5

As a pharmacist, I want to add some clinical context to this discussion on Acid reflux/GERD worsening on GLP-1 .

Building on what JenMemphis said — the evidence base here is robust. The key publications to reference are from the FLOW program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
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