Acid reflux/GERD worsening on GLP-1 — November 2025 — Page 2 | Side Effects & Management

Dr.GutHealth

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Minnesota

Oct 14, 2023 at 4:50 AM#6

PurityPaulOR said:
I have been dealing with this for over a year now, and what I have found is that individual response

Gonna push back on this one. Acid reflux/GERD worsening on GLP-1 is not that straightforward in my experience. I have been on this for 12 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But cost accessibility is a real barrier. We should be honest about that.

1 2VanRx_Mike

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stefan_berlin

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Oct 2024

Berlin, DE

Oct 14, 2023 at 5:07 AM#7

Adding my data to this Acid reflux/GERD discussion:

Metric	Baseline	Month 5	Month 6
Weight	256 lbs	246 lbs	221 lbs
A1C	7.0%	6.0%	5.2%
hsCRP	5.0	4.0	0.6

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.3g/kg/day.

Last edited: Oct 14, 2023 at 8:07 AM

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hank_denver

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Sep 2024

Denver, CO

Oct 14, 2023 at 5:24 AM#8

sean_dublin — wow. This community is amazing.

Last edited: Oct 14, 2023 at 9:24 AM

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Dr.LipidDallas

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Dec 2023

Dallas, TX

Oct 14, 2023 at 5:41 AM#9

Slightly tangential to Acid reflux/GERD but MikeNYC_runner reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

21 9lori_vegas, Dr.PulmRoch, maya_sedona and 18 others

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