+1. This mirrors my journey exactly. The Inter-lab variabilit discussion here is so valuable.

cory_ATX said:

Dad of 2 checking in — I started at 277 lbs and felt like I would tried everything

I respect cory_ATX perspective but I think this oversimplifies things a bit. Re: Inter-lab variability in — the subgroup analyses show meaningful heterogeneity.

I am not saying cory_ATX wrong entirely — just that the picture is more nuanced than a blanket statement. The SURMOUNT data specifically shows baseline BMI-dependent responses.

Reading this thread on Inter-lab variability in hits close to home. Night shift nurse — I started at 263 lbs and felt like I would tried everything.

9 months on tirz and I am a different person. Not just the 38 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Inter-lab variabilit — take the leap. It was the best health decision I have ever made. ❤️

Bookmarked 📌 The Inter-lab variabilit info in this thread is essential. Coming back to this for sure.

PedsEndoPhilly — that is really helpful context on Inter-lab variability in. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.