Happy New Year everyone. Time for our quarterly vendor directory update. This is the Q1 2026 edition — I've compiled community feedback, COA verifications, and shipping reliability data from the last 90 days. As always, this is informational only and not an endorsement of any specific source. Tier 1 — Consistently Verified (3+ independent COAs, 95%+ positive feedback) - CompoundPharm Direct — US-based 503B facility. Semaglutide 5mg/2mL vials. Latest Janoshik COA showed 5.12mg actual content (102.4% label claim). Ships within 2 business days. Price: $149/vial. - PeptideSciencesRx — Domestic lyophilized sema 5mg. HPLC purity 98.7% per December 2025 community-funded test. Requires reconstitution. Price: $129/vial. - TeleMedCompound — Telehealth + pharmacy combo. Prescription included. Semaglutide 2.5mg/mL multi-dose pen. Price: $299/month (includes consultation). Tier 2 — Verified but Limited Data (1-2 COAs, generally positive) - ResearchChem Outlet — Overseas source, lyophilized. One Janoshik test from November showed 4.81mg/5mg vial (96.2%). Shipping takes 10-18 days. Price: $79/vial. - GLP1Direct — Newer domestic source. Single community COA from January showed 97.1% purity. Fast shipping. Price: $139/vial. Tier 3 — Unverified / Insufficient Data - Several sources have been submitted but lack independent testing. I won't list them until we get COAs. Methodology: I track COA submissions, cross-reference batch numbers, monitor the shipping report threads, and weight feedback by account age and post history. Anyone with a fresh account leaving a glowing review gets flagged. Discussion welcome. If you have new COA data, post it and I'll update.

Great work as always Mike. One correction — CompoundPharm Direct raised their price to $159/vial as of January 15th. I placed an order on the 20th and that was the checkout price. Still worth it IMO since their consistency is unmatched. Every single COA I've seen from them has been within 96-104% of label claim. Also want to flag that ResearchChem Outlet changed their packaging. The old vials had blue caps, new ones have grey caps. Same product apparently, but the batch number format changed too. Might be worth getting a fresh COA on the new batches before keeping them in Tier 2.

Can we talk about TeleMedCompound for a sec? I used them in December and the experience was... mixed. The telehealth consultation was literally 4 minutes. Doctor asked me my weight and if I had any thyroid issues, then sent the script. The product itself tested fine (I sent a sample to Janoshik, waiting on results), but the "medical oversight" feels like a checkbox exercise. That said, $299/month all-in when you factor in the prescription cost is actually competitive. My local compounding pharmacy charges $225 for the vial alone, plus $150 for the doctor visit every 3 months. Question for the group: does anyone know if TeleMedCompound's pharmacy is actually a licensed 503B facility or a 503A? Because that matters for quality standards.

TeleMedCompound uses a 503A pharmacy — I checked their state board registration. That means they're compounding per individual prescription, not in bulk under FDA oversight like a 503B. It's not necessarily worse, but the testing requirements are different. 503B facilities have to follow cGMP and report to the FDA. 503A pharmacies are regulated at the state level. For the directory, I think it's worth noting which category each pharmacy falls into. It's a meaningful distinction that most people here don't realize. Also — I'd push GLP1Direct up to Tier 1 soon. I've now submitted two independent COAs for them (different batch numbers from orders placed 3 weeks apart). Both came back at 97%+ purity on HPLC and 98-101% of label claim on content. Their customer service has been solid too. Responded to my questions within a few hours every time.

Good catches all around. Updated the price for CompoundPharm Direct — thanks SemaSourcer. — 503A vs 503B distinction is a great idea. I'll add that to the next revision. And I'll move GLP1Direct to Tier 1 once we get one more independent COA. Our threshold is 3 independent tests — keeps the standard consistent. — the telehealth quality concern is valid. I'm considering adding a "medical oversight" rating to the directory. Quick rubber-stamp consults vs. actual clinical engagement are very different things, even if the product itself is identical. One more thing: I've gotten 3 separate DMs about a source called "PeptidesUSA" — I want to be clear that this vendor is not recommended. Two community members submitted COAs that showed purity below 90%, and one showed an unidentified impurity peak at 7.2 minutes on the HPLC chromatogram. Stay away until they clean up their act.