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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCOA & Analytical TestingBatch-to-batch purity variation — looking for input Page 3

Batch-to-batch purity variation — looking for input

anders_CPH Tue, Jun 4, 2024 at 7:28 AM 19 replies 2,061 viewsPage 3 of 4
paul_denver
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Denver, CO
Jun 4, 2024 at 11:43 AM#11
Dr.GastroMayo said:
Batch-to-batch purity variation is not that straightforward in my experience

This is exactly right. Dr.GastroMayo articulated what I have been trying to explain to my friends for months. The Batch-to-batch purity aspect is what made the difference for me.

Last edited: Jun 4, 2024 at 5:43 PM
31 5Dr.LeslieOBGYN, MikeNYC_runner and 28 others
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alex_tucson
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May 2024
Tucson, AZ
Jun 4, 2024 at 12:00 PM#12

Reading this thread on Batch-to-batch purity hits close to home. Dad of 2 checking in — I started at 281 lbs and felt like I would tried everything.

7 months on tirz and I am a different person. Not just the 56 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Batch-to-batch — take the leap. It was the best health decision I have ever made. ❤️

21 21labquiet_amy, emily_PDX, Dr.SleepRoch and 18 others
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NauseaFreeNow
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Aug 2024
Indiana
Jun 4, 2024 at 12:17 PM#13

Dr.NateNeph — that is really helpful context on Batch-to-batch purity. Follow-up question: how long did you wait before increasing your dose?

I am in a similar situation (week 4) and trying to set realistic expectations.

Last edited: Jun 4, 2024 at 4:17 PM
32 10Dr.PulmRoch, maya_sedona, stefan_berlin and 29 others
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newstart_MO
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Feb 2026
Springfield, MO
Jun 4, 2024 at 12:34 PM#14

To answer alex_tucson's question specifically:

From a clinical standpoint, Batch-to-batch purity is a reasonable concern that deserves a thorough answer.

The short answer: the evidence supports this approach for most patients.

The longer answer involves reviewing the specific clinical trial data relevant to your question, which I am happy to elaborate on if helpful.

13 21TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 10 others
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MikeNYC_runner
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Jul 2024
New York, NY
Jun 4, 2024 at 12:51 PM#15

Bookmarked 📌 The Batch-to-batch info in this thread is essential. Coming back to this for sure.

29 2MASHdoc_SA, GenomicsKate, Dr.ObesityMed and 26 others
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