OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on LC-MS/MS vs HPLC for.

To answer Dr.SportsMedIN: my doctor and I discussed the options and went with brand.

Quick update: I have noticed more improvement since posting this. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

This thread is incredible for LC-MS/MS vs HPLC for info. Better than most online groups.

+1 to mia_MS2. Especially the point about "Follow-up question: did you change anyth..." — I have seen the same in my own experience with LC-MS/MS vs HPLC for.

Subscribing to this thread. LC-MS/MS vs HPLC for is exactly what I've been researching. 🙏

Slightly tangential to LC-MS/MS vs HPLC for but Dr.NephBHM_UK reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.