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Pharmacology & Mechanisms

67 threads · 891 posts
FV
New Tachyphylaxis vs tolerance — September 2026
fiona_VT · Jan 17, 2026
4Replies
548Views
FV
fiona_VT
Jan 17, 2026
SP
New cAMP signaling cascade from GLP-1R activation — what worked for you?
sophie_paris · Jan 13, 2026
13Replies
633Views
SP
sophie_paris
Jan 13, 2026
DT
New Semaglutide fatty acid sidechain — my results so far
DeniseRN_TPA · Jan 9, 2026
10Replies
793Views
DT
DeniseRN_TPA
Jan 9, 2026
DU
Hot GLP-1/GIP receptor co-agonism — anyone have experience?
Dr.NephBHM_UK · Jan 5, 2026
36Replies
1.4KViews
DU
Dr.NephBHM_UK
Jan 5, 2026
A
Study Has anyone dealt with peptide degradation pathways?
Admin · Jan 1, 2026
20Replies
966Views
A
Admin
Jan 1, 2026
K
Guide Receptor internalization and recycling — looking for input
KevinCompounds · Dec 28, 2025
10Replies
753Views
K
KevinCompounds
Dec 28, 2025
D
New Molecular dynamics simulations of GLP-1R binding — need advice
Dr.GutHealth · Dec 23, 2025
8Replies
712Views
D
Dr.GutHealth
Dec 23, 2025
I
Hot GLP-1R allosteric modulators — 12 month update
InsuranceTom · Dec 19, 2025
18Replies
814Views
I
InsuranceTom
Dec 19, 2025

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C
New Incretin effect in healthy vs T2DM — May 2025
CryptoCarl · Dec 14, 2025
6Replies
681Views
C
CryptoCarl
Dec 14, 2025
ZA
New Enteroendocrine L-cell biology — what worked for you?
ZaraB_AL · Dec 9, 2025
11Replies
925Views
ZA
ZaraB_AL
Dec 9, 2025
T
New Structure-function of tirzepatide — my results so far
TomTeleRx · Dec 4, 2025
12Replies
930Views
T
TomTeleRx
Dec 4, 2025
D
Hot Can someone explain how this drug works like I am not a scientist — anyone have experience?
DadBodDave · Nov 29, 2025
27Replies
1.2KViews
D
DadBodDave
Nov 29, 2025
P
Study Has anyone dealt with why does it stop working after a while for some people?
PeptideChemSF · Nov 24, 2025
27Replies
1.1KViews
P
PeptideChemSF
Nov 24, 2025
D
Guide So the drug literally changes your brain?? That is wild — looking for input
Dr.ObesityMed · Nov 19, 2025
8Replies
820Views
D
Dr.ObesityMed
Nov 19, 2025
D
New Is there a simple version of how sema vs tirz are different — need advice
Dr.KarenChen · Nov 13, 2025
10Replies
833Views
D
Dr.KarenChen
Nov 13, 2025
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