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Pharmacology & Mechanisms

67 threads · 891 posts
FV
New Tachyphylaxis vs tolerance — September 2026
fiona_VT · Apr 14, 2026
4Replies
548Views
FV
fiona_VT
Apr 14, 2026
SP
New cAMP signaling cascade from GLP-1R activation — what worked for you?
sophie_paris · Apr 10, 2026
13Replies
633Views
SP
sophie_paris
Apr 10, 2026
DT
New Semaglutide fatty acid sidechain — my results so far
DeniseRN_TPA · Apr 6, 2026
10Replies
793Views
DT
DeniseRN_TPA
Apr 6, 2026
DU
Hot GLP-1/GIP receptor co-agonism — anyone have experience?
Dr.NephBHM_UK · Apr 2, 2026
36Replies
1.4KViews
DU
Dr.NephBHM_UK
Apr 2, 2026
A
Study Has anyone dealt with peptide degradation pathways?
Admin · Mar 29, 2026
20Replies
966Views
A
Admin
Mar 29, 2026
K
Guide Receptor internalization and recycling — looking for input
KevinCompounds · Mar 25, 2026
10Replies
753Views
K
KevinCompounds
Mar 25, 2026
D
New Molecular dynamics simulations of GLP-1R binding — need advice
Dr.GutHealth · Mar 20, 2026
8Replies
712Views
D
Dr.GutHealth
Mar 20, 2026
I
Hot GLP-1R allosteric modulators — 12 month update
InsuranceTom · Mar 16, 2026
18Replies
814Views
I
InsuranceTom
Mar 16, 2026

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C
New Incretin effect in healthy vs T2DM — May 2025
CryptoCarl · Mar 11, 2026
6Replies
681Views
C
CryptoCarl
Mar 11, 2026
ZA
New Enteroendocrine L-cell biology — what worked for you?
ZaraB_AL · Mar 6, 2026
11Replies
925Views
ZA
ZaraB_AL
Mar 6, 2026
T
New Structure-function of tirzepatide — my results so far
TomTeleRx · Mar 1, 2026
12Replies
930Views
T
TomTeleRx
Mar 1, 2026
D
Hot Can someone explain how this drug works like I am not a scientist — anyone have experience?
DadBodDave · Feb 24, 2026
27Replies
1.2KViews
D
DadBodDave
Feb 24, 2026
P
Study Has anyone dealt with why does it stop working after a while for some people?
PeptideChemSF · Feb 19, 2026
27Replies
1.1KViews
P
PeptideChemSF
Feb 19, 2026
D
Guide So the drug literally changes your brain?? That is wild — looking for input
Dr.ObesityMed · Feb 14, 2026
8Replies
820Views
D
Dr.ObesityMed
Feb 14, 2026
D
New Is there a simple version of how sema vs tirz are different — need advice
Dr.KarenChen · Feb 8, 2026
10Replies
833Views
D
Dr.KarenChen
Feb 8, 2026
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