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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPharmacology & MechanismsHas anyone dealt with why does it stop working after a while for some people? Page 4

Has anyone dealt with why does it stop working after a while for some people?

PeptideChemSF Mon, Nov 24, 2025 at 12:51 AM 27 replies 1,132 viewsPage 4 of 6
JennaRN
Senior Member
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Mar 2024
Colorado
Online
Nov 24, 2025 at 6:31 AM#16

Congrats Dr.ObesityMed!! You should be so proud of yourself. 🎉

12 1Dr.KarenChen, Dr.NateNeph, PharmD_Rodriguez and 9 others
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DoseLogDan
Member
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567
Feb 2025
Montana
Nov 24, 2025 at 6:48 AM#17

Just wanted to say — for anyone reading this Has anyone dealt thread who is feeling discouraged: it gets better. The first 6 weeks are the hardest. Hang in there. 💪

33 18Dr.AddMedPHL, newstart_MO, mia_MS2 and 30 others
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mike.trainer_LA
Senior Member
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Apr 2024
Los Angeles, CA
Nov 24, 2025 at 7:05 AM#18

+1. This mirrors my journey exactly. The Has anyone dealt discussion here is so valuable.

25 6mia_MS2, LeilaHI, marcus_mpls and 22 others
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tyler_CSCS
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Jun 2024
Phoenix, AZ
Nov 24, 2025 at 7:22 AM#19

Just wanted to say — for anyone reading this Has anyone dealt thread who is feeling discouraged: it gets better. The first few weeks are the hardest. Hang in there. 💪

34 3amy_econ_NJ, bbq_ray_KC, oliver_london and 31 others
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jim_asheville
Member
289
1,234
Aug 2024
Asheville, NC
Nov 24, 2025 at 7:39 AM#20

Subscribing to this thread. Has anyone dealt with why is exactly what I've been researching. 🙏

37 16LarryQC_SD, wanda_boise, NurseAsh_DET and 34 others
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