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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPharmacology & MechanismsHas anyone dealt with why does it stop working after a while for some people? Page 4

Has anyone dealt with why does it stop working after a while for some people?

PeptideChemSF Thu, Feb 19, 2026 at 12:51 AM 27 replies 1,132 viewsPage 4 of 6
JennaRN
Senior Member
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Mar 2024
Colorado
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Feb 19, 2026 at 6:31 AM#16

Congrats Dr.ObesityMed!! You should be so proud of yourself. 🎉

19 4Dr.KarenChen, Dr.NateNeph, PharmD_Rodriguez and 16 others
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DoseLogDan
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567
Feb 2025
Montana
Feb 19, 2026 at 6:48 AM#17

Just wanted to say — for anyone reading this Has anyone dealt thread who is feeling discouraged: it gets better. The first 6 weeks are the hardest. Hang in there. 💪

27 17Dr.AddMedPHL, newstart_MO, mia_MS2 and 24 others
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mike.trainer_LA
Senior Member
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Apr 2024
Los Angeles, CA
Feb 19, 2026 at 7:05 AM#18

+1. This mirrors my journey exactly. The Has anyone dealt discussion here is so valuable.

11 9mia_MS2, LeilaHI, marcus_mpls and 8 others
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tyler_CSCS
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Jun 2024
Phoenix, AZ
Feb 19, 2026 at 7:22 AM#19

Just wanted to say — for anyone reading this Has anyone dealt thread who is feeling discouraged: it gets better. The first few weeks are the hardest. Hang in there. 💪

23 23amy_econ_NJ, bbq_ray_KC, oliver_london and 20 others
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jim_asheville
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289
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Aug 2024
Asheville, NC
Feb 19, 2026 at 7:39 AM#20

Subscribing to this thread. Has anyone dealt with why is exactly what I've been researching. 🙏

36 19LarryQC_SD, wanda_boise, NurseAsh_DET and 33 others
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