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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPharmacology & MechanismsWhy does it stop working after a while for some people — anyone have experience? Page 8

Why does it stop working after a while for some people — anyone have experience?

kim_atl_prep Thu, Sep 18, 2025 at 5:27 PM 38 replies 2,109 viewsPage 8 of 8
tane_welly
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Sep 2024
Wellington, NZ
Sep 19, 2025 at 4:47 AM#36

Subscribing to this thread. Why does it stop working is exactly what I've been researching. 🙏

38 6GraceAZ_72, carl_compliance, DanielChem_CHI and 35 others
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josh_phd_bmore
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1,678
Jul 2024
Baltimore, MD
Sep 19, 2025 at 5:04 AM#37
laura_annarbor said:
Better than most online groups

This is exactly right. laura_annarbor articulated what I have been trying to explain to my doctor for months. The Why does it stop working aspect is the most important factor.

21 7Dr.ObesityLA, NurseKim_ATL, paul_denver and 18 others
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SaraMom3
Member
456
2,345
Aug 2024
Ohio
Sep 19, 2025 at 5:21 AM#38

Exactly this. My pharmacist said the same thing about Why does it stop.

Last edited: Sep 19, 2025 at 9:21 AM
40 20KetoKyle, CanadaChris, ZaraB_AL and 37 others
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PeptideChemSF
Senior Member
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Jan 2024
San Francisco, CA
Sep 19, 2025 at 5:38 AM#39
tom_AK said:
Night shift nurse — I started at 299 lbs and felt like I would tried everything

This is exactly right. tom_AK articulated what I have been trying to explain to my friends for months. The Why does it stop working aspect is what made the difference for me.

Last edited: Sep 19, 2025 at 9:38 AM
43 19ricardo_MIA, BrianDallas92, labquiet_amy and 40 others
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hans_munich
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Jul 2024
Munich, DE
Sep 19, 2025 at 5:55 AM#40

Can confirm — identical experience.

33 3emma_london, tammy_FL, Dr.LipidDallas and 30 others
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