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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesDo the heart benefits go away if I stop taking it? — anyone have experience? Page 2

Do the heart benefits go away if I stop taking it? — anyone have experience?

LibrarianMeg Fri, Jan 16, 2026 at 2:10 PM 7 replies 975 viewsPage 2 of 2
marco_milano
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Jan 16, 2026 at 5:00 PM#6

Congrats LibrarianMeg!! Keep going — you're doing incredible. 🎉 👏

32 12kevin_tulsa, Dr.PainCLE, mike_mealprep and 29 others
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PharmD_Rodriguez
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Jan 16, 2026 at 5:17 PM#7

Clinical perspective on Do the heart benefits go away if I stop:

I have managed over 200 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

43 14TinaHashiRN, robert_kc, dan_philly and 40 others
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NurseLeah_Nash
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Jan 16, 2026 at 5:34 PM#8

Subscribing to this thread. Do the heart benefits go is exactly what I've been researching. 🙏

34 12PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 31 others
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TinaHashiRN
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Raleigh, NC
Jan 16, 2026 at 5:51 PM#9

Reading this thread on Do the heart benefits go hits close to home. Dad of 2 checking in — I started at 289 lbs and felt like I would tried everything.

15 months on tirz and I am a different person. Not just the 64 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Do the heart — take the leap. It was the best health decision I have ever made. ❤️

30 2Admin, Dr.Martinez, mike_mod and 27 others
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emma_london
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London, UK
Jan 16, 2026 at 6:08 PM#10
marco_milano said:
Keep going — you're doing incredible

This is exactly right. marco_milano articulated what I have been trying to explain to my doctor for months. The Do the heart benefits go aspect is the most important factor.

Last edited: Jan 17, 2026 at 12:08 AM
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