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ForumsCardiovascular OutcomesHeart failure hospitalization reduction on semaglutide — looking for input Page 3

Heart failure hospitalization reduction on semaglutide — looking for input

marcus_mpls Wed, Sep 10, 2025 at 6:31 PM 28 replies 1,408 viewsPage 3 of 6
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Sep 10, 2025 at 10:46 PM#11

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

Last edited: Sep 11, 2025 at 2:46 AM
41 11PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 38 others
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Dr.SurgeonPGH
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Sep 10, 2025 at 11:03 PM#12

Slightly tangential to Heart failure but Dr.GastroMayo reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

27 21TomTeleRx, DoseLogDan, SleepFixSam and 24 others
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cory_ATX
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Sep 10, 2025 at 11:20 PM#13
mel_PDX said:
Follow-up question: how long did you wait before increasing your dose

This is exactly right. mel_PDX articulated what I have been trying to explain to my doctor for months. The Heart failure aspect is the most important factor.

19 8mona_PHX, andrew_nyc, Dr.EndoEP and 16 others
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Dr.DermMIA
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Sep 10, 2025 at 11:37 PM#14

Saving this for reference. Top-tier content.

11 23PeptideChemSF, A1cHero_PHX, Dr.RenalNash and 8 others
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dan_philly
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Sep 10, 2025 at 11:54 PM#15

Adding my data to this Heart failure discussion:

MetricBaselineMonth 5Month 8
Weight278 lbs218 lbs203 lbs
A1C7.2%6.0%5.4%
hsCRP7.04.01.2

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.5g/kg/day.

Last edited: Sep 11, 2025 at 2:54 AM
15 5EndoResFellow, PharmacoVig_BOS, SurmountFan_IN and 12 others
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