Jan 9, 2024 at 1:41 PM#36
Saving this for reference. Quality thread.
36 19laura_annarbor, JenMemphis, pat_auckland and 33 others
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Jan 9, 2024 at 1:58 PM#37
Want to share my personal experience related to Heart rate increase on sema since I think it might help others in a similar situation.
I started my GLP-1 journey in October 2024 at 277 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.
Now, 16 months later: I am down 72 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Heart rate increase aspect specifically was something that made a big difference in my journey.
This community helped me every step of the way.
26 23PharmHunterJen, TomTeleRx, DoseLogDan and 23 others
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Jan 9, 2024 at 2:15 PM#38
Relevant to Heart rate increase on sema — here is my latest bloodwork comparison:
Key improvements: A1C 8.4% → 5.5%, triglycerides 193 → 93 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
41 17mark_tokyo, hans_munich, jason_sac26 and 38 others
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Sigma-Aldrich — Research-Grade Standards
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Shop Reference StandardsJan 9, 2024 at 2:32 PM#39
Want to share my personal experience related to Heart rate increase on sema since I think it might help others in a similar situation.
I started my GLP-1 journey in March 2025 at 249 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.
Now, 8 months later: I am down 79 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Heart rate increase aspect specifically was something that made a big difference in my journey.
This forum was my go-to resource throughout.
15 4RickReta_CO, PharmHunterJen, TomTeleRx and 12 others
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Jan 9, 2024 at 2:49 PM#40
Dr.RaviCardio — that is really helpful context on Heart rate increase on. Follow-up question: did you change anything about your diet at the same time?
I am in a similar situation (month 2) and trying to set realistic expectations.
Last edited: Jan 9, 2024 at 5:49 PM
8 13kate.chem, DataDave, Dr.GutHealth and 5 others
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